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Updated: Mar 30, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
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Genotype-Specific Steroid Profiles Associated With Aldosterone-Producing Adenomas

Tracy Ann Williams1, Mirko Peitzsch2, Anna S Dietz2

  • 1From the Medizinische Klinik und Poliklinik IV (T.A.W., A.S.D., M.B., A.R., Y.R., F.B., M.R.) and Klinische Radiologie (M.T.), Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany; Division of Internal Medicine and Hypertension, Department of Medical Sciences, University of Turin, Turin, Italy (T.A.W.); Institute of Clinical Chemistry and Laboratory Medicine (M.P., G.E.) and Department of Internal Medicine III (J.W.M.L., G.E.), Technische Universtät Dresden, Dresden, Germany; and Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands (T.D., J.W.M.L., J.D.). Tracy.Williams@med.uni-muenchen.de Martin.Reincke@med.uni-muenchen.de.

Hypertension (Dallas, Tex. : 1979)
|November 18, 2015
PubMed
Summary

A distinct steroid signature in blood plasma can differentiate subtypes of aldosterone-producing adenoma (APA). This finding may help identify patients suitable for adrenal venous sampling, improving primary aldosteronism diagnosis.

Keywords:
adrenal glandsaldosteronehyperaldosteronismliquid chromatographytandem mass spectrometry

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