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Updated: Aug 14, 2026

Induction and Monitoring of Adoptive Delayed-Type Hypersensitivity in Rats
Published on: October 1, 2007
[Anticonvulsant Hypersensitivity Syndrome: A Case Report]
Felipe Valderrama Escudero1, Laura Elisa Montoya González2
1Médico psiquiatra, Profesor vinculado en pregrado y posgrado, Universidad CES, Medellín, Colombia.
Abstract:
DRESS syndrome (skin reaction with eosinophilia and systemic symptoms) is an idiosyncratic drug reaction characterized by rash, fever, lymphadenopathy, and internal organ dysfunction. This case report is on a patient with bipolar affective disorder who presented with a systemic inflammatory response associated with the use of valproic acid, and an important activation of symptoms when used with other drugs with a different pharmacological action mechanism. The diagnosis of DRESS syndrome is primarily by exclusion, and its detection may be difficult, which could potentially become fatal for the patient.
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