Related Experiment Video
Updated: Mar 30, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Successful treatment of exertional heat stroke using continuous plasma diafiltration
Natsumi Inoue1, Akira Sato1, Yasuhiro Ikawa1
1Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Abstract:
We report a case of severe exertional heat stroke with multiple organ failure successfully treated with continuous plasma diafiltration (CPDF). PDF effectively removed proinflammatory cytokines, and simultaneously, supported liver function. Furthermore, CPDF therapy showed beneficial effects on multiple organ functions. These features suggest that it is a primary treatment option for exertional heat stroke with multiple organ failure. J. Clin. Apheresis 31:490-492, 2016. © 2015 Wiley Periodicals, Inc.
Related Concept Videos
Continuous Renal Replacement Therapy
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Acute Kidney Injury V: Interprofessional Care
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

