Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoregulation of Blood Flow01:17

Autoregulation of Blood Flow

8.8K
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
8.8K
Glomerular Filtration Rate and its Regulation01:28

Glomerular Filtration Rate and its Regulation

6.4K
The Glomerular Filtration Rate (GFR) is a measure of kidney function, reflecting the volume of filtrate formed per minute in the kidneys. On average, GFR is approximately 125 mL/min in males and 105 mL/min in females. Maintaining a relatively constant GFR is essential for the kidneys to effectively regulate body fluid homeostasis and maintain extracellular stability.
GFR regulation involves two primary intrinsic controls: the myogenic and tubuloglomerular feedback mechanisms.
The myogenic...
6.4K
Neural Regulation of Blood Pressure01:18

Neural Regulation of Blood Pressure

8.5K
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
8.5K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

4.8K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
4.8K
Blood Flow01:29

Blood Flow

77.9K
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
77.9K
Blood Pressure01:30

Blood Pressure

5.6K
Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Minocycline modulates hippocampal BDNF-PSD95 and glial inflammatory protein signaling to alleviate chronic restraint stress-induced depressive- and anxiety-like behaviors.

International journal of biological macromolecules·2026
Same author

Relationship between oral microbiota and chronic kidney disease: facts and perspectives.

Journal of oral microbiology·2026
Same author

<i>Dendrobium huoshanense</i> Ameliorates Sleep Deprivation-Induced Ileal Mucus Barrier Dysfunction by Regulating Steroid Hormone Biosynthesis and the HPA Axis in Rats.

Metabolites·2026
Same author

Nondestructive determination of ash content in wheat flour via terahertz time-domain spectroscopy.

Frontiers in plant science·2026
Same author

The Role of Melatonin and Chronotherapy in the Treatment of Circadian Rhythm Disruption and Depression.

Current neuropharmacology·2026
Same author

Hydrogel delivery platform of engineered apoptotic vesicles for ischemic stroke therapy.

Journal of nanobiotechnology·2026

Related Experiment Video

Updated: Mar 30, 2026

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
07:12

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

10.0K

Ocular Blood Flow Autoregulation Mechanisms and Methods.

Xue Luo1, Yu-Meng Shen1, Meng-Nan Jiang1

  • 1Eye Center, Renmin Hospital of Wuhan University, Wuhan University, Wuhan, Hubei 430060, China.

Journal of Ophthalmology
|November 18, 2015
PubMed
Summary

Ocular blood flow ensures the eye receives oxygen and nutrients. Autoregulation maintains this flow despite pressure changes, but dysregulation is a risk factor for eye diseases like glaucoma.

More Related Videos

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
11:26

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression

Published on: December 10, 2014

12.9K
Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

19.4K

Related Experiment Videos

Last Updated: Mar 30, 2026

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
07:12

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

10.0K
Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
11:26

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression

Published on: December 10, 2014

12.9K
Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

19.4K

Area of Science:

  • Ophthalmology and Physiology

Background:

  • Ocular blood flow is vital for supplying oxygen and nutrients to the eye.
  • Local blood vessel resistance regulates ocular blood distribution, adapting to metabolic demands.
  • Autoregulation maintains constant ocular blood flow despite fluctuations in ocular perfusion pressure.

Purpose of the Study:

  • To review methods for measuring ocular blood flow.
  • To discuss the roles of myogenic and neurogenic mechanisms in ocular blood flow regulation.
  • To describe ocular blood flow regulation in the context of ocular diseases.

Main Methods:

  • Review of direct and indirect techniques for measuring ocular blood flow.
  • Discussion of physiological mechanisms influencing ocular blood flow.
  • Analysis of ocular blood flow regulation in disease states.

Main Results:

  • Ocular blood flow autoregulation is a key protective mechanism.
  • Dysregulation of ocular blood flow is an independent risk factor for ocular diseases.
  • Ocular perfusion pressure significantly impacts the progression of retinopathies.

Conclusions:

  • Understanding ocular blood flow dynamics and regulation is crucial for managing eye health.
  • Ocular blood flow measurement techniques and regulatory mechanisms are essential knowledge for ophthalmologists.
  • Ocular blood flow dysregulation is implicated in the pathogenesis of major eye diseases, highlighting the need for further research.