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Relation of Stroke Risk Factors with Specific Stroke Subtypes and Territories
Farhad Assarzadegan1, Hanif Tabesh2, Arya Shoghli2
1Dept. of Neurology, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.
Insights
This study links stroke risk factors to specific causes and brain regions affected. Identifying these connections aids in more effective stroke prevention strategies.
Area of Science:
- Neurology
- Cardiology
- Public Health
Background:
- Risk factors for ischemic stroke are known, but their links to stroke causes and affected brain areas are less understood.
- This study explores the relationship between stroke risk factors and cerebrovascular attack (CVA) etiologies and specific ischemic brain regions.
Purpose of the Study:
- To investigate the distribution of ischemic stroke risk factors.
- To determine the connections between these risk factors and diverse CVA etiologies.
- To identify associations with specific ischemic regions within the brain.
Main Methods:
- Retrospective cross-sectional study analyzing data from Imam Hossein Medical Center, Tehran, Iran.
- Included patients with a confirmed diagnosis of CVA, excluding hemorrhagic strokes.
- Data collected from archived medical records between March 2010 and September 2012.
Main Results:
- 1011 patients (48.2% male, 51.8% female, mean age 68.91±13.54) were analyzed.
- Atrial fibrillation (AF), valvular heart disease (VHD), and dilated cardiomyopathy were linked to cardioembolic stroke.
- Diabetes mellitus (DM), carotid artery stenosis, and dyslipidemia (DLP) were associated with macroangiopathic stroke.
- Ischemic heart disease (IHD), AF, and VHD correlated with middle cerebral artery (MCA) strokes.
- DM and carotid artery stenosis were linked to posterior cerebral artery (PCA) strokes.
Conclusions:
- Understanding the impact of each risk factor on different stroke etiologies and territories can improve stroke prevention.
- Findings provide a foundation for future research to confirm the pathophysiology of these associations.
Background:
Although the risk factors of ischemic strokes are well defined, there is slight information about their relations with the etiologies of ischemic strokes. This study investigated the distribution of ischemic stroke risk factors and their connections to diverse etiologies of cerebrovascular attack (CVA) and specific ischemic regions of brain.
Methods:
In this cross sectional study, we analyzed the data of patients with definite diagnosis of CVA, excluding hemorrhagic strokes, registered in Imam Hossein Medical Center in Tehran, Iran. The data were collected from entire archived medical records from March 2010 until September 2012, retrospectively.
Results:
Out of 1696 cases a total of 1011 subjects, 487 (48.2%) males and 524 (51.8%) females with mean age of 68.91±13.54 yr were included in the study. Patients suffering from atrial fibrillation (AF), valvular heart disease (VHD), and dilated cardiomyopathy were more prone to develop cardioembolic stroke. Those with diabetes mellitus (DM), carotid artery stenosis and dyslipidemia (DLP) had a higher prevalence of macroangiopathic stroke. Ischemic heart disease (IHD), AF, and VHD were associated with stroke in the brain territory supplied by middle cerebral artery (MCA) while DM and carotid artery stenosis were correspondent with posterior cerebral artery (PCA) stroke.
Conclusion:
The diagnosis of the weight of each risk factor of ischemic strokes on different etiologies and territories of ischemia can assist care providers for a more efficient prevention of strokes. The results of this study can also be a basis for further investigations to corroborate the pathophysiology of such relations.
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