Anesthesia for Potts Shunt in a Child with Severe Refractory Idiopathic Pulmonary Arterial Hypertension

Ashley Eggers1, Gregory J Latham, Jeremy Geiduschek

  • 1From the Departments of *Anesthesiology and Pain Medicine, †Pediatric Cardiology, and ‡Pediatric Cardiovascular Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington.

A & a Case Reports
|November 19, 2015
PubMed

Insights

A surgical Potts shunt offers a promising rescue therapy for children with severe pulmonary arterial hypertension, potentially improving quality and duration of life by creating Eisenmenger physiology.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Surgery
  • Anesthesiology

Background:

  • Childhood idiopathic pulmonary arterial hypertension (IPAH) is a severe, progressive condition.
  • Atrial septostomy is a bridge to lung transplantation for refractory cases.
  • Surgical Potts shunt is an emerging alternative rescue therapy.

Observation:

  • This report details the anesthetic management for a pediatric patient undergoing a surgical Potts shunt.
  • The procedure converts the patient to Eisenmenger physiology.
  • Unique intraoperative anesthetic considerations are highlighted.

Findings:

  • The surgical Potts shunt is a novel intervention for end-stage pulmonary arterial hypertension in children.
  • Initial outcomes suggest promising results for this rescue therapy.
  • Anesthetic management requires careful attention to unique physiological changes.

Implications:

  • The Potts shunt may offer improved quality and duration of life for pediatric patients with pulmonary arterial hypertension.
  • This technique provides a potential alternative to lung transplantation.
  • Further research into anesthetic protocols is warranted for this procedure.

Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
751
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists01:18

Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists

Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
559
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
917