Prolonged and Severe Gestational Thyrotoxicosis Due to Enhanced hCG Sensitivity of a Mutant Thyrotropin Receptor

Anne Laure Coulon1, Frédérique Savagner1, Claire Briet1

  • 1Endocrinologie (A.L.C., O.C.), Centre Hospitalier Universitaire de Grenoble, 38700, La Tronche, France; Département de Biochimie et Génétique (F.S.), Centre Hospitalier Universitaire d'Angers, 49000 Angers, France; Centre National de la Recherche Scientifique 6214/Institut National de la Sante et de la Recherche Medicale 1083 (C.B., M.M., P.R.), Université d'Angers, 49000 Angers, France; Endocrinologie (C.B., M.M., P.R.), Centre de Référence des Maladies Rares de la Réceptivité Hormonale, Centre Hospitalier Universitaire d'Angers, 49000 Angers, France; and Groupe Hospitalier Mutualiste des Eaux-Claires (M.V.), 38028 Grenoble, France.

Abstract

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