Related Experiment Video
Updated: Mar 30, 2026

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
Published on: January 19, 2024
Screening Tool Predicts Future Underimmunization Among a Pediatric Practice in Tennessee
Sarah E Williams1, Ashley Morgan2, Douglas Opel3
1Vanderbilt University School of Medicine, Nashville, TN, USA elizabeth.williams@vanderbilt.edu.
Insights
Parent Attitudes about Childhood Vaccines (PACV) scores predict underimmunization in children. Higher PACV scores correlated with more days unvaccinated, supporting its use in identifying vaccine-hesitant parents.
Area of Science:
- Pediatrics
- Public Health
- Immunology
Background:
- The Parent Attitudes about Childhood Vaccines (PACV) survey aids in identifying vaccine-hesitant parents.
- Previous validation of the PACV survey did not encompass all recommended childhood vaccines.
- Understanding vaccine hesitancy is crucial for maintaining high childhood immunization rates.
Purpose of the Study:
- To compare vaccination rates for all recommended childhood vaccines against PACV scores.
- To assess the predictive validity of the PACV survey for underimmunization in a Tennessee pediatric practice.
- To evaluate the impact of healthcare provider on immunization status.
Main Methods:
- Children were enrolled at a 2-week well visit and vaccination status assessed at 19 months.
- Vaccination rates were measured by the mean percentage of days underimmunized and up-to-date status.
- Parent Attitudes about Childhood Vaccines (PACV) scores were compared with immunization outcomes.
Main Results:
- Higher PACV scores were significantly associated with more days underimmunized (P < .001).
- Elevated PACV scores correlated with being overdue for vaccine doses at 19 months (P < .001).
- No significant difference in immunization status was observed between healthcare providers.
Conclusions:
- The PACV survey demonstrates predictive validity for identifying children at risk of underimmunization.
- PACV scores can be a valuable tool for pediatric practices to address vaccine hesitancy.
- Interventions targeting vaccine-hesitant parents, identified via PACV, may improve childhood vaccination coverage.
Abstract:
The Parent Attitudes about Childhood Vaccines (PACV) survey for identifying vaccine-hesitant parents was recently validated in Washington State but did not include all recommended childhood vaccines. The current study compares vaccination rates for all recommended childhood vaccines and PACV scores at one pediatric practice in Tennessee. Children were enrolled at the 2-week well visit, and vaccination rates were assessed at 19 months of age. Outcomes at 19 months of age included mean percentage of days underimmunized and up-to-date status (yes/no) compared with PACV scores. The impact of provider on immunization status was assessed. Complete vaccination data were available for 158 children of 183 enrolled (86%). Higher PACV scores were associated with more days underimmunized (P < .001) and being overdue for vaccine doses at 19 months of age (P < .001). No difference was seen between providers and up-to-date status. Our study supports the predictive validity of the PACV for underimmunization.
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Preventive Healthcare Services

