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Updated: Aug 8, 2026

16:01
Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis
Published on: January 26, 2015
[Histamine metabolism and its role in central nervous system function]
Summary
This study reviews current data on histamine in the mammalian brain, covering its biosynthesis, storage, release, and inactivation. It also explores how physiologically active substances can regulate brain histamine levels.
Area of Science:
- Neuroscience
- Biochemistry
Context:
- Histamine is a key neurotransmitter in the mammalian brain.
- Understanding histamine's role is crucial for neurological research.
Purpose:
- To consolidate current knowledge on histamine metabolism in the brain.
- To discuss regulatory mechanisms of brain histamine.
Summary:
- This work synthesizes data on the biosynthesis, storage, release, and inactivation of histamine within the mammalian brain.
- It examines the influence of various physiologically active substances on histamine regulation.
Impact:
- Provides a comprehensive overview of brain histamine dynamics.
- Highlights potential targets for modulating neurological functions.
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