Related Experiment Video
Updated: Mar 30, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
Published on: August 21, 2021
DNA Repair
1Center for Integrated Protein Science, CiPSM, Department für Chemie, Ludwig-Maximilians Universität München, Butenandtstrasse 5-13, 81377 München (Germany) http://www.carellgroup.de. thomas.carell@lmu.de.
Abstract:
DNA is constantly damaged by various endogenous and exogenous events. Repair systems constantly scan the genome for DNA lesions and replace damaged and mismatched bases, which finally enables the complex DNA double strand to store genetic information. This year's Nobel Prize in Chemistry was awarded to pioneers in this field, T. Lindahl, P. Modrich, and A. Sancar.
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