[Anticoagulants and inhibitors of thrombocyte function in the long-term treatment of arteriosclerosis]

Oral anticoagulants are suitable for the delay of progression of arteriosclerosis. The therapeutic effect is bound to the stability of the hypocoagulation with values of the thromboplastin time between 15 to 20%. There is a high risk of thrombosis after discontinuation of the therapy. Of the inhibitors of thrombocyte function acetyl salicylic acid preparations are antithrombotically effective. The controversies of dosage high (= 1,500 mg/d) or low (= 20-30 mg/d) are opposed by the concept of the individual dosage via the ASA-test.