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Updated: Mar 30, 2026

Enzyme-linked Immunospot Assay ELISPOT: Quantification of Th-1 Cellular Immune Responses Against Microbial Antigens
Published on: November 23, 2010
Elispot Igra With Purified Protein Derivative Stimulation For Diagnosing Nontuberculous Mycobacterial Cervical
Antti Kontturi1, Tamara Tuuminen, Riitta Karttunen
1From the *Children's Hospital, University of Helsinki and Helsinki University Central Hospital, Helsinki; †Eastern Finland Laboratory Centre Joint Authority Enterprise (ISLAB), Mikkeli District Laboratory, Mikkeli; ‡Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki; and §Laboratory Division (HUSLAB), Helsinki University Central Hospital, Helsinki, Finland.
Abstract:
Childhood cervical lymphadenitis caused by nontuberculous mycobacteria is a diagnostic challenge for the clinician. We present a new promising diagnostic method for childhood nontuberculous mycobacterial lymphadenitis. The modified T-SPOT.TB test with purified protein derivative as an additional antigen is noninvasive with estimated sensitivity and specificity of 1.00 and 0.81, respectively.
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