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Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
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Stem Cell Therapies in Orthopaedic Trauma

Ralph S Marcucio1, Aaron Nauth, Peter V Giannoudis

  • 1*Department of Orthopaedic Surgery, Orthopaedic Trauma Institute, University of California, San Francisco, CA; †Department of Orthopaedic Surgery, University of Toronto, Toronto, ON, Canada; ‡Department of Trauma & Orthopaedic Surgery, University of Leeds, Leeds, United Kingdom; §Leeds Biomedical Research Unit, Chapel Allerton Hospital, Leeds, United Kingdom; ‖Institute of Orthopedics "Carlos E. Ottolenghi," Italian Hospital of Buenos Aires, Argentina; and ¶Cleveland Clinic, Cleveland, OH.

Journal of Orthopaedic Trauma
|November 20, 2015
PubMed
Summary

Stem cells in bone marrow, endosteum, and periosteum are crucial for tissue renewal and fracture repair. This review explores stem cell biology and clinical applications for bone regeneration and healing.

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