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Characteristics of Children With Primary Congenital Glaucoma Receiving Trabeculotomy and Goniotomy
Insights
Trabeculotomy and goniotomy effectively reduce intraocular pressure (IOP) in primary congenital glaucoma (PCG) patients. Trabeculotomy showed greater absolute success with fewer medications compared to goniotomy.
Area of Science:
- Ophthalmology
- Pediatric Glaucoma Surgery
Background:
- Primary congenital glaucoma (PCG) is a severe form of glaucoma requiring surgical intervention.
- Trabeculotomy and goniotomy are common surgical procedures for PCG.
Purpose of the Study:
- To compare trabeculotomy and goniotomy in PCG patients.
- To analyze age at treatment, intraocular pressure (IOP) outcomes, and medication burden.
Main Methods:
- Retrospective chart review of PCG patients from 1998-2012.
- Inclusion criteria: trabeculotomy or goniotomy with >= 9 months follow-up.
- Recorded IOP, medications, and success rates at 1 and 2 years post-surgery.
Main Results:
- Both procedures significantly reduced IOP (29.5% at 1 year, 33.3% at 2 years).
- No significant difference in IOP control between groups.
- Goniotomy group required more medications; trabeculotomy showed higher absolute success rates.
Conclusions:
- Trabeculotomy patients were younger and had higher initial IOP than goniotomy patients.
- Both surgeries effectively lowered IOP for up to 2 years.
- Trabeculotomy achieved better outcomes with less medication burden.
Purpose:
To describe the groups of patients who received trabeculotomy or goniotomy for the treatment of primary congenital glaucoma (PCG) regarding age at treatment, intraocular pressure (IOP) outcome, and medication burden.
Methods:
A retrospective chart review of patients with PCG seen at Rutgers New Jersey Medical School, Newark, New Jersey, from 1998 to 2012 was conducted. Inclusion criteria were patients who received trabeculotomy or goniotomy with at least 9 months of follow-up. Presenting examination, surgical intervention, IOP, and number of medications at 1 and 2 years postoperatively were recorded. Absolute and qualified success, defined as IOP greater than 5 and less than 21 mm Hg without and with medications, respectively, was determined.
Results:
Fifty eyes of 29 patients were diagnosed as having PCG. Of those, 25 eyes received trabeculotomy or goniotomy, with 19 fulfilling inclusion criteria. Average age at the time of trabeculotomy was 8 months versus 21 months for patients undergoing goniotomy. Mean IOP was significantly reduced (P < .001) for both trabeculotomy and goniotomy by 29.5% at 1 year and 33.3% at 2 years. There was no significant difference in IOP control between trabeculotomy and goniotomy groups. Patients in the goniotomy group were treated with significantly more medications before and after surgery compared to patients receiving trabeculotomy (P < .01), resulting in a greater rate of absolute success in trabeculotomy at 1 and 2 years.
Conclusions:
Patients with PCG who underwent trabeculotomy had higher IOP and were treated at an earlier age than those who had goniotomy. Both effectively lowered IOP up to 2 years with greater medication burden in patients receiving goniotomy.
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