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Updated: Mar 30, 2026
Efficient and Consistent Generation of Retinal Pigment Epithelium/Choroid Flatmounts from Human Eyes for Histological Analysis
Published on: October 28, 2022
[Spontaneous separation of epiretinal membrane: Reports of 3 cases]
A Pierru1, J-P Heligon1, G Gendron1
1Centre hospitalier national d'ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France.
Purpose:
Idiopathic epiretinal membranes most commonly develop in patients over 50 years of age. Posterior vitreous detachment seems to play a role in their formation. Epiretinal membranes are uncommon in young subjects. Surgical intervention is indicated in eyes with true functional symptoms and loss of visual acuity.
Method:
We report 3 cases with spontaneous separation of epiretinal membranes imaged by Optical Coherence Tomography.
Results:
All patients reported improvement in functional symptoms after spontaneous separation of the epiretinal membrane. Anatomic recovery with reappearance of the foveolar depression was observed on Optical Coherence Tomography.
Conclusion:
A longer period of observation may be indicated in young patients with epiretinal membrane, due to the higher rate of spontaneous separation.
