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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Cancer02:18

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Cancer Therapies02:49

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Updated: Mar 30, 2026

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
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[Molecular tumour therapy].

C Michel1, A Neubauer1, A Burchert2

  • 1Klinik für Innere Medizin, Schwerpunkt Hämatologie, Onkologie, Immunologie, Universitätsklinikum Gießen und Marburg, Standort Marburg, und Philipps-Universität, Baldingerstr. 1, 35043, Marburg, Deutschland.

Der Internist
|November 21, 2015
PubMed
Summary
This summary is machine-generated.

Molecular tumour therapy offers targeted cancer treatment with fewer side effects than traditional chemotherapy. Advances in molecularly designed drugs, like immune checkpoint inhibitors, are transforming oncology but increase healthcare costs.

Keywords:
Antibodies, monoclonalDrug resistance, neoplasmImmunomodulationProtein kinase inhibitorsToxicity

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Area of Science:

  • Oncology
  • Molecular Biology
  • Pharmacology

Context:

  • Molecular tumour therapy has significantly advanced cancer treatment.
  • Key components include kinase inhibitors and monoclonal antibodies.
  • Challenges like therapy resistance persist in current molecular therapies.

Purpose:

  • To review the advancements and challenges in molecular tumour therapy.
  • To highlight the role of molecularly designed drugs in modern oncology.
  • To discuss the impact of these therapies on cancer treatment and healthcare costs.

Summary:

  • Molecular therapies target cancer cells more specifically, aiming for reduced side effects compared to conventional chemotherapy.
  • Despite successes, overcoming tumour resistance remains a significant hurdle.
  • The development of novel molecular drugs, exemplified by immune checkpoint inhibitors, is reshaping cancer care.

Impact:

  • Molecularly designed drugs are revolutionizing oncological therapeutic practices.
  • These targeted approaches offer improved specificity and potentially fewer side effects.
  • The increasing efficacy of molecular therapies is associated with escalating healthcare expenditures.