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Related Experiment Videos

Colonic and anorectal dysfunction associated with multiple sclerosis.

J P Hinds1, A Wald

  • 1Gastroenterology Unit, Montefiore Hospital, University of Pittsburgh School of Medicine, Pennsylvania.

The American Journal of Gastroenterology
|June 1, 1989
PubMed
Summary
This summary is machine-generated.

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Gastrointestinal issues like constipation and fecal incontinence affect many multiple sclerosis patients. This review covers their causes, symptoms, and treatment options for better bowel management.

Area of Science:

  • Neurology
  • Gastroenterology

Background:

  • Gastrointestinal (GI) symptoms are frequently reported by patients with multiple sclerosis (MS).
  • Constipation and fecal incontinence are prevalent, affecting up to 68% of MS patients.
  • Bowel dysfunction in MS is understudied compared to bladder dysfunction.

Purpose of the Study:

  • To review the clinical features and pathophysiology of constipation and fecal incontinence in multiple sclerosis.
  • To present current treatment options for bowel dysfunction in MS.
  • To offer suggestions for investigating colonic and anorectal dysfunction in this patient population.

Main Methods:

  • Literature review of existing studies on GI symptoms in multiple sclerosis.
  • Analysis of survey data on the prevalence of constipation and fecal incontinence in MS patients.

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  • Synthesis of information on pathophysiology and treatment strategies.

    • Main Results:

    • A high prevalence (68%) of constipation and/or fecal incontinence was reported in a survey of 280 unselected MS patients.
    • Bowel dysfunction in MS is a significant issue often overlooked in clinical practice.
    • Existing research on MS-related bowel dysfunction is limited.

    Conclusions:

    • Constipation and fecal incontinence are common and significant problems in multiple sclerosis.
    • Further research and clinical attention are needed to address bowel dysfunction in MS patients.
    • A systematic approach to investigation and treatment is recommended for managing GI symptoms in MS.