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Aging

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

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Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

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Related Experiment Video

Updated: Mar 30, 2026

Induction and Validation of Cellular Senescence in Primary Human Cells

Induction and Validation of Cellular Senescence in Primary Human Cells

Published on: June 20, 2018

Gerontology in India.

Ramamurti V Panruti¹, Phoebe S Liebig², Jamuna Duvvuru³

¹Centre for Research on Ageing, Department of Psychology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.

The Gerontologist

|November 21, 2015

Summary

India

Keywords:

Aging in India Research and education on aging Status of Indian elders

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Last Updated: Mar 30, 2026

Induction and Validation of Cellular Senescence in Primary Human Cells

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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

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Oral Health Assessment by Lay Personnel for Older Adults

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Area of Science:

Gerontology
Sociology
Public Health

Background:

India's large population (1.22 billion) includes 90 million elderly individuals.
The elderly population relies heavily on family for financial and caregiving support.
Current research on aging in India spans medical, biological, behavioral, and social sciences.

Purpose of the Study:

To outline the current state of aging research and elder care in India.
To identify key challenges and initiatives related to the elderly population in India.

Main Methods:

Review of existing research and policy documents on aging in India.
Analysis of demographic trends and socio-economic factors affecting the elderly.
Examination of governmental and non-governmental organization (NGO) services for seniors.

Main Results:

Aging is an emerging academic discipline, with limited specialized educational programs.
Various national and state agencies, alongside NGOs, provide essential services like housing, daycare, and healthcare.
Policy revisions and new institutions signal growing attention to the needs of older persons.

Conclusions:

India faces significant challenges in ensuring healthcare and financial security for its vast elderly population, particularly the rural and uneducated poor.
Ongoing policy revisions and program implementations aim to address these critical needs.
Further development in specialized education and comprehensive support systems is crucial for India's aging demographic.