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Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
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[Eosinophilic cellulitis: About a new pediatric case].

Saadia Makni1, Rim Kallel1, Hend Chaabène2

  • 1Laboratoire d'anatomie et de cytologie pathologiques, hôpital universitaire Habib Bourguiba, 3029 Sfax, Tunisie.

Annales De Pathologie
|November 21, 2015
PubMed
Summary

Wells' syndrome, a rare pediatric condition, presents as eosinophilic cellulitis with skin lesions. Early diagnosis and topical corticosteroid treatment led to a favorable outcome in a 14-month-old boy.

Keywords:
Cellulite à éosinophilesChildhoodEnfantEosinophilic cellulitisSyndrome de WellsWells’ syndrome

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Area of Science:

  • Dermatology
  • Pediatrics
  • Pathology

Background:

  • Wells' syndrome, also known as eosinophilic cellulitis, is a rare inflammatory skin condition.
  • It is characterized by clinical signs mimicking cellulitis and histological findings of dermal eosinophilic infiltrate with flame figures.
  • The condition is exceptionally uncommon in pediatric patients.

Observation:

  • A 14-month-old boy presented with painful, nodular, brownish lesions on his thigh and foot.
  • He also exhibited multiple erythematous papular and vesicular lesions on his face, limbs, and trunk.
  • These clinical manifestations raised suspicion for Wells' syndrome.

Findings:

  • Biological analyses and histological examination were performed to confirm the diagnosis.
  • Histopathology revealed characteristic eosinophilic infiltration of the dermis with flame figures.
  • The diagnostic findings definitively identified the condition as Wells' syndrome.

Implications:

  • This case highlights the importance of considering Wells' syndrome in pediatric patients presenting with cellulitis-like symptoms.
  • Early diagnosis through clinical and histological evaluation is crucial for appropriate management.
  • The favorable outcome achieved with topical corticosteroids (dermocorticoids) suggests an effective treatment approach for pediatric Wells' syndrome.