: a database of ciliate genome rearrangements
Jonathan Burns1, Denys Kukushkin2, Kelsi Lindblad3
1Department of Ecology and Evolutionary Biology, Princeton University, NJ 08544, USA Department of Mathematics & Statistics, University of South Florida, FL 33620, USA.
Abstract:
Ciliated protists exhibit nuclear dimorphism through the presence of somatic macronuclei (MAC) and germline micronuclei (MIC). In some ciliates, DNA from precursor segments in the MIC genome rearranges to form transcriptionally active genes in the mature MAC genome, making these ciliates model organisms to study the process of somatic genome rearrangement. Similar broad scale, somatic rearrangement events occur in many eukaryotic cells and tumors. The
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