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Updated: Mar 29, 2026
07:09
Isolation of Adipose Tissue Immune Cells
Published on: May 22, 2013
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Adipose Tissue: Sanctuary for HIV/SIV Persistence and Replication
Suresh Pallikkuth1, Mahesh Mohan2
1Department of Microbiology and Immunology, University of Miami Miller School of Medicine, 1580 NW 10th Avenue BCRI 708, Miami, FL 33136, USA.
Trends in Microbiology
|November 22, 2015
Summary
Adipose tissue is a potential reservoir for human immunodeficiency virus (HIV) and a key site of inflammation in chronic HIV infection. New research is exploring ways to reduce this inflammation for better patient outcomes.
Area of Science:
- Immunology
- Virology
- Metabolic Disease
Background:
- Chronic human immunodeficiency virus (HIV) infection is associated with persistent inflammation.
- The role of adipose tissue in HIV pathogenesis is increasingly recognized.
Purpose of the Study:
- To highlight recent findings on adipose tissue as an HIV reservoir.
- To discuss challenges and future research directions for managing adipose inflammation in HIV/SIV infection.
Main Methods:
- Commentary based on recent study findings.
- Review of existing literature on HIV/SIV and adipose tissue.
Main Results:
- Adipose tissue identified as a potential HIV reservoir.
- Adipose tissue is a major site of inflammation during chronic HIV/SIV infection.
Conclusions:
- Targeting adipose inflammation may be a novel therapeutic strategy for HIV/SIV.
- Further research is needed to understand and mitigate adipose tissue inflammation in HIV/SIV infection.
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