Related Experiment Video
Updated: Mar 29, 2026

Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise
Published on: July 14, 2023
Optimization of parameters of Yi Zhi Chan Tuina manipulation promotes peripheral circulation
Objective:
To explore the most effective parameters of Yi Zhi Chan Tuina manipulation for improving peripheral blood circulation.
Methods:
A total of 45 volunteers were recruited from Pudong district in Shanghai, China, from October to December 2010, and randomly divided into nine groups using computer-generated random numbers. Participants received Yi Zhi Chan Tuina manipulation on Chengjin (BL 56) acupoint; each group received a particular combination of manipulation force and treatment time. We used a two-factor, three-level factorial design to examine the effects of force and treatment time on changes in popliteal artery average volume flow, pulsatility index, and vessel diameter to determine the optimal parameter group. Outcomes were assessed at baseline and after Tuina manipulation by interviewers blind to treatment group status.
Results:
After manipulation, two of the nine groups showed an increase in popliteal artery volume flow. An inter-participants effect test showed that for main effect of time, F = 0.331, P = 0.720; for main effect of force, F = 2.934, P = 0.066; and for the force-time interaction effect, F = 1.072, P = 0.385, indicating no interaction between force and time. However, a pairwise comparison of the three levels of time showed that a treatment time of 10 min was significantly more effective than that of 2 min (P = 0.024). A pairwise comparison of light force, medium force, and heavy force showed a statistically significant effect for medium force (P = 0.035).
Conclusion:
Yi Zhi Chan Tuina manipulation with vertical force of 9.31 N for 10 min is most effective in improving peripheral circulation.
Related Concept Videos
Peripheral Artery Disease III: Interprofessional Care
Direct-Acting Cholinergic Agonists: Pharmacological Actions
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Peripheral Artery Disease IV: Nursing Management
Pathophysiology of Cardiac Performance

