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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 10, 2011

Methicillin-resistant staphylococci

C Thornsberry1

  • 1Antimicrobics Investigations Branch, Centers for Disease Control, Atlanta, Georgia.

Clinics in Laboratory Medicine
|June 1, 1989
PubMed

Insights

Methicillin-resistant staphylococci are increasingly common causes of hospital and community infections. These resistant strains often exhibit multi-drug resistance, complicating treatment options.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Staphylococcus aureus and coagulase-negative staphylococci are significant pathogens in both healthcare-associated and community-acquired infections.
  • The prevalence of antimicrobial resistance in staphylococcal infections is a growing global health concern.

Purpose of the Study:

  • To highlight the increasing incidence of resistance to penicillinase-resistant penicillins among staphylococcal species.
  • To underscore the association between methicillin resistance and resistance to multiple antimicrobial classes.

Main Methods:

  • This abstract is based on a review of current epidemiological data and clinical observations regarding staphylococcal infections and antimicrobial resistance patterns.
  • Analysis of trends in nosocomial and community-acquired staphylococcal infections.

Main Results:

  • Staphylococci, including Staphylococcus aureus and coagulase-negative staphylococci, are leading causes of nosocomial infections.
  • There is a consistent rise in resistance to penicillinase-resistant penicillins, such as methicillin and oxacillin.
  • Methicillin-resistant staphylococci frequently display resistance to numerous other antimicrobial agents.

Conclusions:

  • The increasing resistance of staphylococci to methicillin and other antibiotics poses a significant challenge for infection control and treatment.
  • Effective strategies are needed to combat the spread of multi-drug resistant staphylococcal strains.

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