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Updated: Mar 29, 2026

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
Published on: May 25, 2017
Assessment of Clostridium difficile Burden in Patients Over Time With First Episode Infection Following Fidaxomicin
Seth T Housman1, Abrar K Thabit1, Joseph L Kuti1
11Center for Anti-Infective Research and Development,Hartford Hospital,Hartford,Connecticut.
Abstract:
In patients with first episode Clostridium difficile infection treated with vancomycin or fidaxomicin, more patients receiving fidaxomicin achieved at least 2 log10 colony-forming units/g reduction in spores at the follow-up visit (P=.02). Similar to published literature, a higher proportion of patients receiving fidaxomicin demonstrated sustained clinical response.
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