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Updated: Mar 29, 2026

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
Published on: May 22, 2020
IMAGING DIAGNOSIS-VERTEBRAL POLYOSTOTIC LYMPHOMA IN A GERIATRIC DOG
Julie Kornder1, Simon R Platt1, Joe Eagleson1
1Department of Small Animal Medicine & Surgery, College of Veterinary Medicine, University of Georgia, 501 DW Brooks Drive, Athens, GA, 30602.
Abstract:
A 9-year-old spayed female Scottish terrier presented with an 8-day history of progressive paraparesis. Neurological examination suggested a painful T3-L3 myelopathy. Multifocal uniform contrast-enhancing masses involving the vertebral bodies, pedicles, laminae, and spinous processes of two vertebrae and compressing the spinal cord were present on MRI. Fluoroscopic-guided fine needle aspiration of one of the vertebral lesions revealed a predominantly lymphoblastic population of cells compatible with a diagnosis of lymphoma. To the authors' knowledge, this represents the first published case of canine lymphoma with vertebral involvement, characterized with MRI.
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