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Cultivation Methods of Spirochetes from Borrelia burgdorferi Sensu Lato Complex and Relapsing Fever Borrelia
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Relapsing Fever Borreliae: A Global Review

Sally J Cutler1

  • 1School of Health, Sport and Bioscience, University of East London, London E15 4LZ, UK.

Clinics in Laboratory Medicine
|November 24, 2015
PubMed

Insights

Relapsing fever borreliae, historically devastating bacterial infections, remain common in developing nations despite being overshadowed by other diseases. These spirochetes, transmitted by ticks and lice, utilize diverse survival mechanisms.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Epidemiology

Background:

  • Relapsing fever borreliae historically caused significant epidemic and endemic infections.
  • These bacterial spirochetes are now often overlooked, overshadowed by diseases like malaria.
  • Despite diminished recognition, they persist as a common bacterial infection in certain developing regions.

Purpose of the Study:

  • To highlight the continued relevance of relapsing fever borreliae.
  • To underscore their epidemiological significance in specific global contexts.
  • To explore the survival strategies of these resilient spirochetes.

Main Methods:

  • Literature review of historical and current epidemiological data.
  • Analysis of transmission vectors (soft ticks, lice).
  • Examination of microbial survival mechanisms.

Main Results:

  • Relapsing fever borreliae, though less prominent globally, remain a significant public health concern in endemic areas.
  • Transmission occurs via arthropod vectors, primarily soft ticks and lice.
  • The spirochetes possess sophisticated adaptations for survival in various environments.

Conclusions:

  • Relapsing fever borreliae warrant continued attention due to their persistent burden in developing countries.
  • Understanding their transmission and survival mechanisms is crucial for control efforts.
  • Further research is needed to address their impact and develop effective interventions.
Keywords:
Argasid (soft) ticksBorreliaClothing liceEndemic relapsing feverEpidemic relapsing feverLouse-borne relapsing feverPediculus humanusTick-borne relapsing fever

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