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Detection of the pH-dependent Activity of Escherichia coli Chaperone HdeB In Vitro and In Vivo
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Published on: October 23, 2016

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HdeB chaperone activity is coupled to its intrinsic dynamic properties

Jienv Ding1,2, Chengfeng Yang3,2, Xiaogang Niu3,2

  • 1College of Life Sciences, Peking University, Beijing 100871, China.

Scientific Reports
|November 24, 2015
PubMed
Summary

Bacterial acid resistance relies on chaperones like HdeB. Unlike HdeA, HdeB uses internal protein dynamics, not structural changes, for acid protection at pH 4-5, maintaining its dimer form.

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