Technical Refinements in Autologous Hand Rejuvenation
Related Experiment Video
Updated: Mar 29, 2026

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
Published on: May 23, 2025
Nathaniel L Villanueva1, Sean M Hill, Kevin H Small
1Dallas, Texas From the Department of Plastic Surgery, University of Texas Southwestern Medical Center.
Abstract:
The aging hand is characterized by skin changes and soft-tissue deflation, which leads to rhytides, dermal atrophy, and distinct anatomical structures. Soft-tissue deflation and prominent hand anatomy can be corrected with volume augmentation using dermal fillers or lipofilling. Fat transfer volumizes the hand with prolonged durability and efficacy, autologous tissue replacement, and possible dermal regeneration. The senior author's (R.J.R.) technique for hand rejuvenation is described, which uses minimal access and blunt dissection to effectively augment the soft-tissue compartments of the hand. This approach addresses the prominent aged anatomy of the hand, providing excellent contour and aesthetic outcomes.
Related Concept Videos
Tissue Renewal without Stem Cells
However, failure of such a system...
Clinical Applications of Epidermal Stem Cells

