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Updated: Mar 29, 2026

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A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
Published on: March 26, 2019
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[SEPTIC SHOCK IN PATIENT WITH SEVERE HEAD TRAUMA]
Anesteziologiia I Reanimatologiia
|November 25, 2015
Summary
Early detection of sepsis in severe traumatic brain injury (sTBI) patients is crucial. Advanced hemodynamic monitoring and inflammatory marker screening, including interleukins, aid in timely diagnosis and treatment optimization.
Area of Science:
- Critical Care Medicine
- Neuroscience
- Infectious Diseases
Background:
- Severe traumatic brain injury (sTBI) presents complex management challenges.
- Early identification and treatment of complications like sepsis are vital for patient outcomes.
Observation:
- A patient with sTBI developed hyperthermia and cardiovascular collapse.
- Initial sepsis markers were inconclusive, necessitating advanced hemodynamic monitoring (PiCCO) and interleukin (IL-6, IL-2R) assessment.
- Diagnosis of aspiration pneumonia was confirmed via radiological signs, bronchoscopy, and inflammatory markers.
Findings:
- Elevated interleukins confirmed sepsis, despite normal procalcitonin levels.
- Advanced hemodynamic monitoring revealed cardiovascular collapse.
- Treatment with extended antibiotics and continuous veno-venous hemofiltration stabilized the patient.
Implications:
- Integrating advanced hemodynamic monitoring and interleukin profiling can improve sepsis detection in sTBI.
- Optimized treatment strategies are essential for managing inflammatory-toxic conditions in critically ill patients.
- This case highlights the importance of comprehensive monitoring for severe traumatic brain injury complications.

