Related Experiment Video
Updated: Mar 29, 2026

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment
Published on: December 6, 2024
The implementation of a nonpharmacologic protocol to prevent intensive care delirium
Ryan M Rivosecchi1, Sandra L Kane-Gill2, Sue Svec1
1University of Pittsburgh Medical Center, Presbyterian Campus, 200 Lothrop St, Pittsburgh, PA, 15213.
Purpose:
The purpose was to determine if the implementation of an evidence-based nonpharmacologic protocol reduced the percentage of time patients spent delirious in a medical intensive care unit (MICU) that already uses a sedation and mobility protocol.
Materials And Methods:
This was a prospective, pre-post quality improvement project of MICU patients conducted from September 2013 to April 2014. Evidence-based effective nonpharmacologic interventions with nursing education were bundled into the project protocol: music, opening/closing of blinds, reorientation/cognitive stimulation, and eye/ear care.
Results:
Patients were evaluated between September 2013 and April 2014, with 230 and 253 patients being included in the each phase. There was a 50.6% reduction (16.1% vs 9.6%, P < .001) in time spent delirious in the MICU. Incidence of delirium developed was decreased (15.7% vs 9.4%, P = .04). The protocol reduced the odds of developing delirium by 57% (odds ratio, 0.43; P = .005) after controlling for age, Acute Physiology and Chronic Health Evaluation II, mechanical ventilation, and dementia.
Conclusions:
The implementation of a nonpharmacologic delirium prevention protocol resulted in a significant decrease in the percentage of time spent delirious in the MICU while reducing the risk of delirium development. Additional studies with more rigorous study designs need to be completed to further the research of nonpharmacologic interventions with appropriate sedation and mobility protocols.
Insights
Implementing a nonpharmacologic delirium prevention protocol significantly reduced time spent delirious in the medical intensive care unit (MICU). This evidence-based approach also lowered the incidence of delirium development in critically ill patients.
Area of Science:
- Critical Care Medicine
- Gerontology
- Nursing Research
Background:
- Delirium is a common complication in intensive care units, associated with adverse outcomes.
- Existing sedation and mobility protocols may not fully address delirium prevention.
- Nonpharmacologic interventions offer a potential strategy to mitigate delirium.
Purpose of the Study:
- To evaluate the effectiveness of an evidence-based nonpharmacologic protocol in reducing delirium duration in a medical intensive care unit (MICU).
- To assess the impact of the protocol on the incidence of delirium development.
Main Methods:
- A prospective, pre-post quality improvement project involving MICU patients from September 2013 to April 2014.
- Implementation of a bundled nonpharmacologic protocol including music, light management, reorientation, and sensory care.
- Nursing education on evidence-based nonpharmacologic interventions was provided.
Main Results:
- A 50.6% reduction in the percentage of time patients spent delirious was observed (16.1% vs 9.6%, P < .001).
- The incidence of delirium development decreased significantly (15.7% vs 9.4%, P = .04).
- The protocol reduced the odds of developing delirium by 57% (OR, 0.43; P = .005), controlling for covariates.
Conclusions:
- Implementation of the nonpharmacologic delirium prevention protocol led to a significant reduction in delirium time and incidence in the MICU.
- Further rigorous studies are needed to confirm the efficacy of nonpharmacologic interventions within comprehensive care protocols.
More Related Videos
10:38Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
11:50Clinical Practice Protocol of Creative Music Therapy for Preterm Infants and Their Parents in the Neonatal Intensive Care Unit
Published on: January 7, 2020
Related Concept Videos
Acute Coronary Syndrome IV: Interprofessional Care
Alzheimer's Disease: Treatment