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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
Published on: September 21, 2017
Long-Range Charge Transport in Adenine-Stacked RNA:DNA Hybrids
Yuanhui Li1, Juan M Artés1, Joshua Hihath1
1Department of Electrical and Computer Engineering, University of California Davis, Davis, CA, 95616, USA.
Abstract:
An extremely important biological component, RNA:DNA can also be used to design nanoscale structures such as molecular wires. The conductance of single adenine-stacked RNA:DNA hybrids is rapidly and reproducibly measured using the break junction approach. The conductance decreases slightly over a large range of molecular lengths, suggesting that RNA:DNA can be used as an oligonucleotide wire.
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