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A Novel Hemostatic Patch That Stops Bleeding in Cardiovascular and Peripheral Vascular Procedures
Kreg Howk1, Jason Fortier2, Robert Poston3
1Covidien, Medical Affairs, Mansfield, MA.
Annals of Vascular Surgery
|November 25, 2015
Summary
The Veriset hemostatic patch is safe and effective for controlling cardiovascular and peripheral vascular bleeding. This topical agent demonstrated faster hemostasis compared to other treatments in preclinical studies.
Area of Science:
- Surgical innovation
- Biomaterials in medicine
- Vascular surgery
Background:
- Achieving surgical hemostasis is challenging, especially in vascular procedures.
- Existing hemostatic agents are less effective with vigorous bleeding.
- Veriset hemostatic patch is approved for solid organs and soft tissue.
Purpose of the Study:
- To assess the safety and efficacy of the Veriset hemostatic patch.
- Evaluate Veriset in cardiovascular and peripheral vascular procedures.
Main Methods:
- Preclinical study in adult domestic swine.
- Procedures included coronary artery bypass graft (CABG) and carotid arteriotomy.
- Compared Veriset, Surgicel Nu-Knit, and standard of care for bleeding control.
Main Results:
- Veriset showed no adverse effects on vessel diameter or serum chemistry.
- Veriset was completely absorbed within 28 days.
- Veriset achieved faster hemostasis in carotid arteriotomy and CABG anastomosis compared to Surgicel Nu-Knit.
Conclusions:
- Veriset hemostatic patch demonstrates comparable safety to Surgicel Nu-Knit.
- Veriset is effective in controlling cardiovascular and peripheral vascular bleeding.
- Rapid topical application suggests clinical utility in various surgical settings.
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