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ReSure Sealant for Pars Plana Vitrectomy Wound Closure
Ophthalmic Surgery, Lasers & Imaging Retina
|November 25, 2015
Summary
ReSure Sealant, a polyethylene glycol hydrogel, shows promise for sealing sclerotomy wounds after pars plana vitrectomy. This safe and quick method may be suitable for select cases.
Area of Science:
- Ophthalmology
- Biomaterials Science
Background:
- ReSure Sealant is an FDA-approved ocular sealant previously validated for clear corneal incisions post-cataract surgery.
- This study investigates the novel application of ReSure Sealant for managing sclerotomy site leakage following 23-gauge pars plana vitrectomy (PPV).
Observation:
- A case report details the use of ReSure Sealant to successfully close leaking sclerotomies in a 70-year-old female patient undergoing PPV for epiretinal membrane.
- The sealant was applied to both scleral and conjunctival incisions after careful drying of the surgical site.
Findings:
- The polymerized sealant forms a biocompatible polyethylene glycol (PEG) hydrogel, composed of 89% water and 9.44% PEG.
- Polyethylene glycol is a non-toxic, inert synthetic material appropriate for medical applications.
Implications:
- ReSure Sealant presents a potentially safe and efficient method for managing sclerotomy wound closure in specific ophthalmic surgical scenarios.
- Further research may explore the broader utility of this sealant in various vitreoretinal surgical procedures to prevent or manage wound leakage.
