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Updated: Mar 29, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Home functioning profiles in people with multiple sclerosis and their relation to disease characteristics and
Mandy W M Fong1, Eun-Jeong Lee2, Kathy Sheppard-Jones3
1Department of Neurology, Washington University, St. Louis, MO, USA.
Background:
For people with multiple sclerosis (MS), limitations in performing activities of daily living can have a significant impact on personal independence, residential safety, and quality of life. In this study we explored the utility of the Home Functioning Scale in identifying home functioning profiles and generating rehabilitation interventions.
Objective:
The objective of this study was to determine whether distinctive and meaningful home functioning profiles could be identified among adults with MS based on Home Functioning Scale scores.
Methods:
Home Functioning Scale scores and additional data from a representative national sample of 3,834 adults were analyzed. We used cluster analysis and MANOVA to identify and evaluate group differences.
Results:
Three distinct home functioning profiles emerged in the analysis: (1) minimal impairment (31.1% of participants); (2) moderate impairment (52.4%); and (3) severe impairment (16.5%). The three groups exhibited significant differences on demographic and MS related characteristics, perceived cognitive function, perceived MS impact on physical and psychological function, and life satisfaction.
Conclusion:
The profile characteristics of the identified groups are presented and the implications of the results for rehabilitation practitioners and the investigation of home functioning in activities of daily living are discussed.

