Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

7.2K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From dividing to dormant: embracing the full activity spectrum for environmental microorganisms.

Microbiology and molecular biology reviews : MMBR·2026
Same author

BRCore: an R package implementing flexible selection of core taxa using contribution to Bray-Curtis dissimilarity and neutral model fitting.

Microbiology resource announcements·2026
Same author

Lab Launches-New Leaders, New Discoveries.

mSystems·2026
Same author

Lab Launches-New Leaders, New Discoveries.

mSphere·2026
Same author

Sex-specific microbiome-host interactions: from infection to chronic disease-call for papers.

mSystems·2026
Same author

Evaluating the legacy of drought exposure on root and rhizosphere bacterial microbiomes over two plant generations.

Microbiology spectrum·2026
Same journal

The cell cloud: Adopting systems biology concepts in the era of single-cell immunology.

PLoS biology·2026
Same journal

Disinhibitory signaling enables flexible coding of top-down information in cortical networks.

PLoS biology·2026
Same journal

Correction: Cdc42 interacts with chaperone Ydj1 to enhance its stability and partitioning during asymmetric cell division and aging in yeast.

PLoS biology·2026
Same journal

Towards globally equitable bioinformatics adoption.

PLoS biology·2026
Same journal

The human claustrum supports cognitive networks for externally and internally driven task demands.

PLoS biology·2026
Same journal

Unusual decay: Recombination loss leads to splicing errors in green algae.

PLoS biology·2026
See all related articles

Related Experiment Video

Updated: Mar 29, 2026

An Experimental and Bioinformatics Protocol for RNA-seq Analyses of Photoperiodic Diapause in the Asian Tiger Mosquito, Aedes albopictus
12:10

An Experimental and Bioinformatics Protocol for RNA-seq Analyses of Photoperiodic Diapause in the Asian Tiger Mosquito, Aedes albopictus

Published on: November 30, 2014

14.0K

Computing Workflows for Biologists: A Roadmap.

Ashley Shade1,2, Tracy K Teal2,3

  • 1Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.

Plos Biology
|November 25, 2015
PubMed
Summary
This summary is machine-generated.

This guide simplifies computational analysis for biologists working with large datasets. It provides practical steps for data management and analysis to ensure reproducible biological research.

More Related Videos

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.7K
A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

Published on: May 28, 2021

10.7K

Related Experiment Videos

Last Updated: Mar 29, 2026

An Experimental and Bioinformatics Protocol for RNA-seq Analyses of Photoperiodic Diapause in the Asian Tiger Mosquito, Aedes albopictus
12:10

An Experimental and Bioinformatics Protocol for RNA-seq Analyses of Photoperiodic Diapause in the Asian Tiger Mosquito, Aedes albopictus

Published on: November 30, 2014

14.0K
Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.7K
A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

Published on: May 28, 2021

10.7K

Area of Science:

  • Biology
  • Bioinformatics
  • Computational Biology

Background:

  • Large biological datasets are increasingly common.
  • Computational analysis can be challenging for biologists without extensive training.

Purpose of the Study:

  • To provide a beginner-friendly, step-by-step guide for computational analysis of large biological datasets.
  • To promote reproducible research practices in biology.

Main Methods:

  • Focus on foundational data management principles.
  • Outline practical approaches for performing computational analyses.
  • Recommendations tailored for the biologist end-user.

Main Results:

  • A clear, actionable framework for analyzing large biological datasets.
  • Empowers biologists to conduct their own computational analyses.
  • Enhances the reproducibility of biological research findings.

Conclusions:

  • Effective data management and guided computational workflows are crucial.
  • Biologists can confidently perform complex data analyses with the right approach.
  • This guide facilitates robust and reproducible biological research.