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Excimer laser keratoplasty. Part 1: Basic concepts.

G K Lang1, E Schroeder, J W Koch

  • 1Department of Ophthalmology and Eye Clinic, University Erlangen-Nuemberg, West Germany.

Ophthalmic Surgery
|April 1, 1989
PubMed
Summary
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This study shows that using an excimer laser with an open mask system for corneal surgery creates high-quality trephinations and grafts. This advanced excimer laser keratoplasty technique offers superior wound geometry in both human and pig eyes.

Area of Science:

  • Ophthalmology
  • Surgical Technology
  • Biomedical Engineering

Background:

  • Excimer lasers are utilized in ophthalmic surgery.
  • Novel surgical systems aim to improve corneal graft procedures.

Purpose of the Study:

  • To evaluate the efficacy of a new open mask system with an ophthalmic excimer laser for keratoplasty.
  • To assess the quality of corneal trephinations and grafts produced by this technique.

Main Methods:

  • A commercially available ophthalmic excimer laser and a new open mask system were employed.
  • Noncontact, nonthermal excimer laser keratoplasty was performed on 20 human and 40 pig cadaver eyes.
  • Circular penetrating corneal trephinations and grafts were created at 193 nm wavelength.
  • Microscopic analysis (light, scanning, and transmission electron microscopy) was conducted.

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Main Results:

  • The excimer laser trephination demonstrated high quality with smooth, parallel wound margins.
  • The corneal grafts exhibited superior wound configuration and geometry.
  • Both human and pig cadaver eyes showed comparable results.

Conclusions:

  • The open mask system facilitates high-quality excimer laser keratoplasty.
  • This technique produces precise corneal trephinations and grafts with excellent wound characteristics.
  • The findings support the potential of this method for advanced corneal surgical procedures.