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Updated: Aug 10, 2026

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
Published on: March 11, 2016
[Diagnostic and therapeutic changes in renal developmental anomalies detected in childhood]
Abstract:
The authors diagnosed 40 renal malformations during 2 years investigated and 2 years control period. On the basis of analysing their patients they came to the conclusion that after the introduction of intrauterine routine ultrasound examinations and screening of childhood risk group the number of recognised renal malformations increased significantly (32 in the investigated and only 8 in the control period). Furthermore the age of patients at the time of diagnosing shifted to the early postnatal period, and the number of patients diagnosed on the basis of the positive urinary investigations decreased significantly. But the intrauterine routine ultrasound investigation at presently applied examination system can consider only one-third of fetal renal malformations. And also an important fact that the increased number of considered patients came from the increasing of patients who have needed operation and did not increase the number of infants who have needed only conservative therapy. According to the small surgical complications they concluded that the risk of the early surgical intervention does not seem to be higher than in case of postponed ones. On the basis of clinical observation with childhood risk group arising the necessarity of the non invasive postnatal routine screening.
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