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Updated: Mar 29, 2026

In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy
Published on: November 11, 2017
Ultra-widefield retinal imaging through a black intraocular lens
Imran H Yusuf1, Timothy H M Fung1, Chetan K Patel1
1From the Oxford Eye Hospital, West Wing, John Radcliffe Hospital, Oxford, United Kingdom.
Purpose:
To evaluate the feasibility of ultra-widefield retinal imaging in patients with near infrared (IR)-transmitting black intraocular lenses (IOLs).
Setting:
Oxford Eye Hospital, Oxford, United Kingdom.
Design:
Laboratory evaluation of a diagnostic technology with interventional case report.
Methods:
The field of retinal imaging through a Morcher poly(methyl methacrylate) (PMMA) black IOL was determined in a purpose-built adult schematic model eye with the HRA2 Spectralis confocal scanning laser ophthalmoscope using standard imaging, Staurenghi retina lens-assisted imaging, and ultra-widefield noncontact imaging. Retinal imaging using each modality was then performed on a patient implanted with another Morcher PMMA black IOL model.
Results:
Ultra-widefield noncontact imaging and lens-assisted imaging captured up to 150 degrees of field (versus 40 degrees with a standard confocal scanning laser ophthalmoscope). Ultra-widefield retinal images were successfully acquired in a patient eye with a black IOL.
Conclusions:
This study has identified the first ultra-widefield retinal imaging modalities for patients with near IR-transmitting black IOLs. Should larger studies confirm this finding, noncontact ultra-widefield confocal scanning laser ophthalmoscopy might be considered the gold standard imaging technique for retinal surveillance in patients with near IR-transmitting black IOLs.
Financial Disclosure:
No author has a financial or proprietary interest in any material or method mentioned.
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