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Updated: Mar 29, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Cardiac arrest and therapeutic hypothermia
Michael G Silverman1, Benjamin M Scirica1
1Cardiovascular Division, Department of Medicine, Brigham and Women׳s Hospital, Boston, MA.
Abstract:
Therapeutic hypothermia for patients who remain comatose following resuscitation from a cardiac arrest improves both survival and neurologic outcomes. Although this therapy has been incorporated into the guidelines for routine post-resuscitation care and has been in clinical use for over a decade, significant questions and controversies remain. In this review, we discuss these questions in the context of the current evidence and provide a practical framework to help guide clinicians.
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