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Pregnancy and Thoracic Aortic Disease: Managing the Risks.

Shaynah Wanga1, Candice Silversides2, Annie Dore3

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Summary

Women of childbearing age with aortopathies face increased risks during pregnancy due to hemodynamic and hormonal changes. Preconception counseling and specialized multidisciplinary care are crucial for managing these risks.

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Area of Science:

  • Cardiovascular Medicine
  • Genetics
  • Obstetrics & Gynecology

Background:

  • Common aortopathies in women of childbearing age include bicuspid aortic valve, Marfan syndrome, and Turner syndrome.
  • Pregnancy-induced hemodynamic and hormonal shifts elevate the risk of aortic dilatation or dissection in affected women.
  • Hypertension further exacerbates the risk of aortic complications during pregnancy.

Purpose of the Study:

  • To review risk assessment and management strategies for pregnant women with aortopathies.
  • To highlight the importance of preconception counseling for women with known aortopathies.
  • To emphasize the need for specialized multidisciplinary team follow-up throughout pregnancy and postpartum.

Main Methods:

  • This is a review article.
  • It synthesizes current knowledge on aortopathies in women of childbearing age.
  • It discusses risk stratification and management protocols.

Main Results:

  • Pregnancy poses significant risks for women with various aortopathies.
  • Early identification and management are key to preventing aortic complications.
  • Multidisciplinary care is essential for optimal outcomes.

Conclusions:

  • Women with aortopathies require careful preconception counseling.
  • Serial monitoring by a specialized team is vital during and after pregnancy.
  • Proactive risk assessment and management can improve maternal and fetal outcomes.