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Lower Levels of Antiretroviral Therapy Enrollment Among Men with HIV Compared with Women - 12 Countries, 2002-2013
Insights
Gender inequity in antiretroviral therapy (ART) access persists, with women accessing treatment more than men in many countries. Increased male engagement in HIV testing and treatment is crucial for equitable outcomes and reducing HIV transmission.
Area of Science:
- Public Health
- Epidemiology
- Global Health
Background:
- Equitable access to antiretroviral therapy (ART) for people with human immunodeficiency virus (HIV) is a global health priority.
- Gender disparities in accessing life-saving HIV treatment remain a significant challenge in many regions.
Purpose of the Study:
- To evaluate gender equity in ART access among adults (≥15 years) in 12 countries between 2002 and 2013.
- To compare the ratio of women to men accessing ART with the estimated ratio of HIV-infected women to men in the general population.
Main Methods:
- Analysis of 765,087 adult ART patient medical records across 12 countries in five geographic regions.
- Comparison of annual ART enrollment ratios (women to men) with Joint United Nations Programme on HIV/AIDS (UNAIDS) estimates of HIV prevalence ratios.
Main Results:
- In 10 African countries and Haiti, the ratio of women to men among new ART enrollees significantly exceeded UNAIDS estimates by 23%-83%.
- The ratio of women to men in ART enrollment increased more sharply over time than HIV prevalence ratios in six African countries and Haiti.
- ART access shows a persistent gender gap favoring women in many high HIV burden settings.
Conclusions:
- Increased ART coverage among men is essential to reduce HIV-related morbidity and mortality.
- Enhanced HIV testing, linkage-to-care services for men, and 'test-and-treat' strategies are needed to address gender inequity in ART access.
- Reducing gender disparities in ART access is critical for effective HIV control and prevention efforts.
Abstract:
Equitable access to antiretroviral therapy (ART) for men and women with human immunodeficiency virus (HIV) infection is a principle endorsed by most countries and funding bodies, including the U.S. President's Emergency Plan for AIDS (acquired immunodeficiency syndrome) Relief (PEPFAR) (1). To evaluate gender equity in ART access among adults (defined for this report as persons aged ≥15 years), 765,087 adult ART patient medical records from 12 countries in five geographic regions* were analyzed to estimate the ratio of women to men among new ART enrollees for each calendar year during 2002-2013. This annual ratio was compared with estimates from the Joint United Nations Programme on HIV/AIDS (UNAIDS)(†) of the ratio of HIV-infected adult women to men in the general population. In all 10 African countries and Haiti, the most recent estimates of the ratio of adult women to men among new ART enrollees significantly exceeded the UNAIDS estimates for the female-to-male ratio among HIV-infected adults by 23%-83%. In six African countries and Haiti, the ratio of women to men among new adult ART enrollees increased more sharply over time than the estimated UNAIDS female-to-male ratio among adults with HIV in the general population. Increased ART coverage among men is needed to decrease their morbidity and mortality and to reduce HIV incidence among their sexual partners. Reaching more men with HIV testing and linkage-to-care services and adoption of test-and-treat ART eligibility guidelines (i.e., regular testing of adults, and offering treatment to all infected persons with ART, regardless of CD4 cell test results) could reduce gender inequity in ART coverage.
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