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Updated: Mar 29, 2026

High-Throughput Protein Crystallization via Microdialysis
Published on: March 3, 2023
A Superhydrophobic Surface Templated by Protein Self-Assembly and Emerging Application toward Protein Crystallization
Aiting Gao1, Qian Wu1, Dehui Wang1
1Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710119, China.
Abstract:
A proteinaceous superhydrophobic material for facile protein crystallization is reported. The lysozyme phase transition is rationally manipulated to form a reliable superhydrophobic coating on virtually arbitrary material surfaces with good thermostability and mechanical robustness. Such a surface exhibits a fascinating capability to drive protein crystallization, and the protein crystal array can be facilitated in a large area at an ultralow protein concentration.

