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Updated: Mar 29, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Implication of lncRNAs in pathogenesis of esophageal cancer
Wei-Wei Tang1, Qingquan Wu2, Su-Qing Li1
1Department of Surgical Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.
Abstract:
Long non-coding RNAs (lncRNAs), transcripts as longer than 200 nt in length with a great number of varieties in human genomics, play important roles in the regulation of genetics and epigenetics including gene transcription and post-transcription. Increasing evidence have demonstrated the upregulation of lncRNAs in tumorigenesis and metastasis of esophageal cancer (EC), a type of malignant tumors particularly in Asia. In this review, we briefly discuss the profiles and functions of lncRNAs involved in the progression of EC, which may provide a new approach to improve EC diagnosis and treatment.
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