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A novel 10-hydroxycamptothecin-glucoside from the fruit of Camptotheca acuminata
1a Department of Pharmaceutical Technology , College of Biological Engineering, Wuhan Polytechnic , Wuhan , China.
Abstract:
Glycosides were isolated from the fruit of Camptotheca acuminata and identified using NMR, MS, UV and IR spectrometries. 10-O-(1-β-D-glycosyl) camptothecin (1) was identified for the first time in a natural material. In addition, compounds 2-4 were firstly reported from the fruits of C. acuminata and indentified as syringaresinol-4, 4'-O-bis-β-D-glucoside (2), hyperoside (3) and pumiloside (4), respectively. Two known compounds, vincoside-lactam (5) and strictosidinic acid (6), were also obtained.
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