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MRM Microcoil Performance Calibration and Usage Demonstrated on Medicago truncatula Roots at 22 T

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Optimizing accuracy and precision of micro-coil localization in active-MR tracking.

Barret Robert Daniels¹, Ronald Pratt², Randy Giaquinto¹

¹Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 5033, Cincinnati, OH 45229 USA; University of Cincinnati, 2901 Woodside Drive, Cincinnati, OH 45221 USA.

Magnetic Resonance Imaging

|November 28, 2015

Summary

Combining centroid peak detection and micro-transmit tracking with Hadamard Multiplexing and Phase-field Dithering significantly enhances magnetic resonance (MR) tracking accuracy and precision for medical applications.

Keywords:

Active device tracking Centroid pixel method Interventional MRI MR catheter tracking MR tracking Micro-transmit tracking

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Area of Science:

Medical Imaging
Biomedical Engineering
Physics

Background:

Active magnetic resonance (MR) tracking is crucial for precise medical interventions.
Existing strategies like Hadamard Multiplexing and Phase-field Dithering have limitations in accuracy and precision.

Purpose of the Study:

To evaluate the combined effect of a centroid peak detection algorithm and micro-transmit tracking on active-MR tracking accuracy and precision.
To assess improvements when these methods are integrated with Hadamard Multiplexing and Phase-field Dithering.

Main Methods:

Modeled the dipole magnetic field of a solenoid tracking coil and simulated MR spin excitation.
Experimentally assessed MR-tracking accuracy and precision using a lumenless micro-coil in a 1.5-T MRI scanner for 576 orientations.
Employed centroid pixel method and micro-transmit tracking, alongside Hadamard Multiplexing and Phase-field Dithering.

Main Results:

The simultaneous application of centroid pixel method, micro-transmit tracking, Phase-field Dithering, and Hadamard Multiplexing achieved high MR tracking accuracy (0.52±0.41 mm) and precision (0.34 mm).
The combined approach resulted in a tracking error smaller than the micro-coil's size, even without an internal signal source.

Conclusions:

Micro-transmit tracking and the centroid pixel method demonstrably improve MR tracking accuracy and precision.
The integration of these techniques with Phase-field Dithering and Hadamard Multiplexing offers superior performance over using the latter two methods alone.