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Effect of Sleep State and Position on Obstructive Respiratory Events Distribution in Adolescent Children
Karim El-Kersh1, Rodrigo Cavallazzi1, Paras M Patel1
1Department of Medicine, Division of Pulmonary, Critical Care and Sleep Disorders Medicine, University of Louisville, Louisville, KY.
Summary
Obstructive respiratory events in adolescents are more frequent during rapid eye movement (REM) sleep and when lying on their back (supine position). This finding is crucial for understanding sleep-related breathing issues in this age group.
Area of Science:
- Pediatric Sleep Medicine
- Respiratory Physiology
- Adolescent Health
Background:
- Obstructive respiratory events can significantly impact adolescent health and development.
- Understanding the distribution of these events across different sleep stages and body positions is critical for diagnosis and treatment.
Purpose of the Study:
- To investigate the influence of sleep state (REM vs. NREM) and body position (supine vs. non-supine) on obstructive respiratory events in adolescents aged 12-18 years.
Main Methods:
- Retrospective analysis of 150 adolescents (12-18 years) with an apnea-hypopnea index (AHI) > 1/h.
- Exclusion of subjects on REM sleep-suppressant medications or with genetic/craniofacial anomalies.
Main Results:
- Obstructive events were significantly more common during REM sleep (median REM OAHI: 8.9/h) compared to NREM sleep (median NREM OAHI: 3.2/h).
- Supine positioning led to more obstructive events (median supine OAHI: 6.55/h) than non-supine positions (median non-supine OAHI: 2.94/h).
- African American adolescents exhibited higher REM obstructive event rates than white adolescents.
Conclusions:
- Adolescent obstructive respiratory events predominantly occur during REM sleep.
- The supine position is associated with a higher frequency of obstructive respiratory events in this population.
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