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Updated: Mar 29, 2026

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
Published on: April 13, 2015
An overlooked parameter in coronary slow flow phenomenon: whole blood viscosity
Mehmet Serkan Cetin1, Elif Hande Ozcan Cetin1, Ugur Canpolat1
1Turkey Yuksek Ihtisas Education & Research Hospital, Cardiology Clinic, Ankara, Turkey.
Aims:
We aimed to assess the relationship between coronary slow flow phenomenon (CSFP) and whole blood viscosity (WBV).
Materials & Methods:
Two hundred patients with CSFP and 200 subjects with normal coronary arteries as control group were enrolled. WBV was calculated from hematocrit and plasma protein concentration at low shear rate (LSR) (0.5 s(-1)) and high shear rate (HSR) (208 s(-1)) by a validated equation.
Results:
CSFP patients had significantly higher WBV for LSR and HSR. The mean corrected TIMI frame count was highest in the highest tertile group for both shear rates. Corrected TIMI frame count revealed a significant relationship with WBV for LSR (r = 0.562) and HSR (r = 0.611). At multivariate analysis, WBV at LSR and HSR were independent predictors of CSFP.
Conclusion:
WBV seemed to have a significant and an independent predictor of CSFP.
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