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Long-term outcomes of pericardiectomy for constrictive pericarditis
Murat Biçer1, Bülent Özdemir2, İris Kan3
1Department of Cardiovascular Surgery, Uludağ University Medical Faculty, Bursa, Turkey. mbicer23@yahoo.com.
Insights
Pericardiectomy offers functional improvement for constrictive pericarditis patients, but carries significant risks. Long-term survival is achievable, though careful patient selection is crucial for better outcomes.
Area of Science:
- Cardiology
- Thoracic Surgery
- Medical Research
Background:
- Constrictive pericarditis involves chronic pericardial thickening, leading to disability.
- Pericardiectomy is a surgical treatment option for this condition.
Purpose of the Study:
- To evaluate the long-term outcomes of pericardiectomy for constrictive pericarditis.
- Assess functional status, survival rates, and complications post-surgery.
Main Methods:
- Retrospective analysis of 47 patients undergoing pericardiectomy (Sept 1992 - May 2014).
- Collected and analyzed demographic, pre-, intra-, and postoperative data.
- Long-term outcomes including survival and recurrence were tracked.
Main Results:
- Tuberculosis was the most common etiology (46.8%).
- 80% of patients showed functional status improvement (at least one NYHA class).
- In-hospital mortality was 2.1%, with a late mortality of 23.4%. Actuarial survival at 1, 5, and 10 years was 91%, 85%, and 81% respectively. No recurrence requiring reoperation was observed.
Conclusions:
- Pericardiectomy is linked to substantial morbidity and mortality.
- Patients with malignancy, low cardiac output, or requiring reoperation face higher mortality and poorer functional recovery.
- Careful patient selection is recommended for optimal pericardiectomy outcomes.
Background:
Constrictive pericarditis is a rare and disabling disease that can result in chronic fibrous thickening of the pericardium. The purpose of this study was to evaluate the long-term outcomes following treatment of constrictive pericarditis by pericardiectomy.
Methods:
Between September 1992 and May 2014, 47 patients who underwent pericardiectomy for constrictive pericarditis were retrospectively examined. Demographic, pre-, intra- and postoperative data and long-term outcomes were analyzed.
Results:
Thirty of the patients were male, the mean age was 45.8 ± 16.7. Aetiology of constrictive pericarditis was tuberculosis in 22 (46.8 %) patients, idiopathic in 15 (31.9 %), malignancy in 3 (6.4 %), prior cardiac surgery in 2 (4.3 %), non-tuberculosis bacterial infections in 2 (4.3 %), radiotherapy in 1 (2.1 %), uraemia in 1 (2.1 %) and post-traumatic in 1 (2.1 %). The surgical approach was achieved via a median sternotomy in all patients except only 1 patient. The mean operative time was 156.4 ± 45.7 min. Improvement in functional status in 80 % of patients' at least one New York Heart Association (NYHA) functional class was observed. In-hospital mortality rate was 2.1 % (1 of 47 patients). The cause of death was pneumonia leading to progressive respiratory failure. The late mortality rate was 23.4 % (11 of 47 patients). The mean follow-up time was 61.2 ± 66 months. The actuarial survival rates were 91 %, 85 % and 81 % at 1, 5 and 10 years, respectively. Recurrence requiring a repeat pericardiectomy was developed in no patient during follow-up.
Conclusion:
Pericardiectomy is associated with high morbidity and mortality rates. Cases with neoplastic diseases, diminished cardiac output, cases in need of reoperation are expected to have high mortality rates and less chance of functional recovery.
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