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Updated: Mar 29, 2026

Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids
Published on: October 14, 2019
Surgical Treatment of Small Bowel Neuroendocrine Tumors
Heather A Farley1, Rodney F Pommier2
1Department of Surgery, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Mail Code L 619, Portland, OR 97329, USA.
Abstract:
Neuroendocrine tumors of the small bowel are rare, slow-growing malignancies that commonly metastasize to nodes at the root of the mesentery and the liver. Liver metastases are associated with carcinoid syndrome. Mesenteric nodal masses can cause bowel obstruction, intestinal angina, or variceal hemorrhage. Patients die of liver failure or bowel obstruction. Primary resection is associated with improved survival rates. Selected patients may benefit from liver debulking operations. Liver resection has excellent survival rates even in the event of an incomplete resection, as well as improvement in hormonal symptoms. Radiofrequency ablation can help to preserve hepatic parenchyma during resection.

