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Pediatric Salivary Gland Malignancies
Robert A Ord1, Eric R Carlson2
1Department of Oral and Maxillofacial Surgery, Baltimore College of Dental Surgery, University of Maryland and the Greenbaum Cancer Institute, Suite 1402, 650, West Baltimore Street, Baltimore, MD 21201, USA.
Oral and Maxillofacial Surgery Clinics of North America
|November 29, 2015
Summary
Pediatric malignant salivary gland tumors are rare but have better survival rates than adult cases. Surgical excision with negative margins is the primary treatment for these rare childhood cancers.
Area of Science:
- Pediatric Oncology
- Surgical Oncology
- Tumor Biology
Background:
- Malignant salivary gland tumors are exceptionally rare in children.
- Despite rarity, the proportion of malignant tumors is higher in pediatric patients compared to adults.
- Pediatric patients exhibit improved survival outcomes relative to adult counterparts.
Purpose of the Study:
- To provide a comprehensive review of pediatric malignant salivary gland tumors.
- To discuss current understandings of demographics, etiology, and management strategies.
- To analyze treatment outcomes and survival data for this rare pediatric condition.
Main Methods:
- Review of current literature on pediatric malignant salivary gland tumors.
- Synthesis of information regarding epidemiology, causative factors, and treatment approaches.
- Analysis of patient outcomes, including survival rates and prognostic indicators.
Main Results:
- Pediatric malignant salivary gland tumors are infrequent but present with a higher malignancy rate than in adults.
- Surgical excision aiming for negative margins is the cornerstone of treatment.
- Pediatric patients generally experience better survival outcomes compared to adults.
Conclusions:
- Malignant salivary gland tumors in children, though rare, require specialized management.
- Effective treatment relies on complete surgical resection.
- Ongoing research is crucial for improving the understanding and outcomes of these rare pediatric malignancies.
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